The mindfulness group reported less lower-back pain

In Spain, the group receiving nine sessions reported less stress and a better physical SF-36 subscale score than with usual care.

How we make these readings

The key idea

The mindfulness group reported less lower-back pain and a better score on one physical-function measure, but blood markers did not show the same pattern.

The study, in plain language

Persistent lower-back pain can affect both movement and mood. At several centers in Spain, the team compared a mindfulness-based stress-reduction program with usual care, examining self-reports alongside some biological measures. Of 96 people randomized, 70 completed the study and were analyzed.

During treatment, the program group reported less pain, a better score on one physical-function subscale, less stress, and fewer depressive symptoms, along with a favorable signal in sleep quality. Blood cortisol did not differ between groups, and only IL-1β fell within the program group, which had started with higher levels of several markers. IL-6 also showed no difference. The Roland-Morris disability scale showed no between-group difference. These results do not support a general reduction in inflammation or improvement across all functional measures. In addition, there was no post-treatment measurement, and participants knew their group.

What they found

  • During the program, people reported less lower-back pain than those receiving usual care.
  • They also had a better score on the SF-36 physical-function subscale, less stress, and fewer depressive symptoms. Another disability scale did not distinguish the groups.
  • Cortisol and IL-6 showed no between-group differences. IL-1β fell within the program group, which had higher baseline levels of some markers.

Something to think about

If pain stays with you for months, how does it affect your mood, sleep, and movement? This study looked at all of them, not only the pain score.

How they studied it

At several centers in Spain, 96 people with chronic disc-related lower-back pain were randomized; 70 completed the study and were analyzed. The team compared nine mindfulness sessions with usual care. Pain, function, psychological state, sleep quality, and signs of inflammation were measured during treatment.

What the study cannot show

  • There was no post-treatment measurement; patients and clinicians were not blinded; participants’ usual therapy was not recorded; there was no group receiving another intervention; and the sample was small. Differences among patients and centers may also affect results.
  • It does not establish that mindfulness alone caused all changes, that it reduces inflammation in a clinically meaningful way, or that it replaces evaluation or treatment for lower-back pain.

The original study

The effect of mindfulness on the inflammatory, psychological and biomechanical domains of adult patients with low back pain: A randomized controlled clinical trial

PLOS ONE, 17(11), e0276734. · DOI 10.1371/journal.pone.0276734. Published .

Study authors (1)

Gustavo G. Diez; Eduardo Anitua; Nazareth Castellanos; Carmelo Vázquez; Purificación Galindo-Villardón; Mohammad H. Alkhraisat.

DOI: 10.1371/journal.pone.0276734

Source under CC BY 4.0. English adaptation and explanation by PaperFlow, with AI assistance. The text has been reorganized for a general audience; it is not the complete paper and does not imply endorsement by its authors.

One study alone does not represent a field's consensus. Educational content does not replace professional advice. Report a possible error.